Sunday, January 27, 2008

OHTS findings

OcHTN patients:
  • At 5 years: observation group = 9.5%, treatment group = 4.4% developed glaucoma
  • At 7 years, observation group = 13%, treatment group = 4.4% developed glaucoma

Risk factors for developing POAG identified:
  • advanced age
  • race (the prevalence of glaucoma is higher in blacks than in whites)
  • sex (male)
  • larger vertical cup-to-disc ratios
  • greater pattern standard deviation on Humphrey visual fields
  • thinner central cornea measurements.
Other risks factors:
  • IOP fluctuation and Diurnal curves -- peak IOP at night
  • systemic disease
  • optic nerve hemorrhages
  • PPA
  • zone alpha -- further from the disc; chorioretinal/pigment crescent
  • zone beta -- adjacent to disc; scleral crescent (more associated with glaucoma)
  • sleep apnea
  • high myopia (structural changes make it hard to evaluate nerve shape)

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