Corneal transplant examinations

Signs/symptoms of graft rejection

• redness
• irritation,
• light sensitivity
• FBS
• blurred vision
• general inflammatory response (vascular dilation and transudation)
• cellular infiltration -- sub-epithelial infiltrates ~0.5 mm scattered throughout the donor tissue only (respond to topical steroids)
• tissue edema
• stromal rejection -- neovascularization and stromal infiltrates
• endothelial rejection -- KPs scattered across the endothelium or in a linear form advancing in from the peripheral cornea; causes edema of stroma and epithelium