Fuch's heterochromic iridocyclitis

• the affected eye presents as the lighter eye (90% of the time) due to iris atrophy due to chronic inflammation
• 10% of the time the darker iris is the affected eye due to progressive atrophy within the anterior iris and stroma, revealing the posterior iris pigment epithelium
• 4-5% of uveitis cases
• chronic recurring mild A/C reaction, usually unilateral
• small, round, grey-white keratic precipitates across entire endothelium (including superiorly, unlike other inflammatory conditions)
• often with iris nodules and transillumination
• synechiae are rare

• assocated with mildly elevated occurrences of glaucoma, vitreous opacities and cataracts
• Amsler's sign: a classic finding of hyphema occurring immediately after a paracentesis

Treatment

• often do not require treatment
• topical cycloplegic and corticosteroids if symptomatic, although true resolution of the inflammation may never be achieved
• often have a low grade of A/C reaction that proves to be resistant to topical corticosteroids